Skin gets vitamins, nutrients, and other requirements from its rich blood supply. Every square inch of the skin contains eight feet of blood vessels. The majority of the blood supply resides inside the dermis or second skin layer, and the skin gets one-half to two-thirds of the body’s blood supply. The superficial, visible skin layer (epidermis) doesn’t have any direct blood supply. As a matter of fact, it doesn’t need much from the blood supply because it mostly consists of dead or dying skin cells.